Get the latest offers and updates from Lewis.

Sign up to receive email alerts on Lewis weekly ads, coupons, in-store events and more.

Lewis Family Drug - Sisseton

925 SD HWY 10, Sisseton, SD 57262

Explore This Store

925 SD HWY 10
Sisseton, SD 57262

Main Phone:

605-698-2222

Store Hours


Mon: 9am - 6pm
Tue: 9am - 6pm
Wed: 9am - 6pm
Thu: 9am - 6pm
Fri: 9am - 6pm
Sat: 9am - 1pm
Sun: Closed
Local Deals Directions

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

View More

Stop by your local Lewis Family Drug, conveniently located in Sisseton, and find a large selection everyday essentials, all at affordable prices.

Need to order a prescription? Give our pharmacy a call or quickly and safely refill your prescription with Online or Mobile Refills.

Upcoming Events

Get the latest offers and updates from Lewis.