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Your first stop for over 79 years.

Since 1942, shoppers have trusted family-owned Lewis as their neighborhood store and pharmacy. With 57 stores conveniently located throughout South Dakota, Iowa and Minnesota! In addition to quality prescription and non-prescription drugs, Lewis has a huge selection of everyday basics, plus name brands and specialty items—always at affordable prices.

You’ll find everything on your list along with a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

At Lewis, we promise you’ll be greeted with exceptional prices, friendly service and great products every time you walk through our doors. Make Lewis your first stop for all your family’s needs.

Meet Our Executive Team

It takes a dedicated team to keep Lewis bringing you everyday savings. Meet Our Executive Team.

Questions or Comments?

If you have any questions or concerns, please don’t hesitate to let us know. Contact us today. A Lewis representative will reach out to you shortly.

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Looking Back: Lewis Drug

On Feb. 10, 1942, South Dakota’s first self-service drugstore opened at 309 S. Phillips Ave. It was a little store called Lewis, and it occupied the space now run by CH Patisserie just south of Minerva’s.

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