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Lewis - 10th & Cliff, Sioux Falls

1301 E 10th St. Suite 100 , Sioux Falls, SD 57103

Explore This Store

1301 E 10th St. Suite 100
Sioux Falls, SD 57103

Main Phone:

605-367-2000

Store Hours


Mon: 8am - 9pm
Tue: 8am - 9pm
Wed: 8am - 9pm
Thu: 8am - 9pm
Fri: 8am - 9pm
Sat: 8am - 9pm
Sun: 8am - 6pm​
Weekly Ad Directions

Pharmacy

Pharmacy Phone:

605-367-2310

Pharmacy Hours


Mon: 9am - 8pm
Tue: 9am - 8pm
Wed: 9am - 8pm
Thu: 9am - 8pm
Fri: 9am - 8pm
Sat: 9am - 6pm
Sun: 10am - 6pm

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

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Stop in at your Sioux Falls Lewis and find a large selection of everyday basics. Take advantage of affordable prices on name brands and specialty items at our convenient location at 10th Street & Cliff Avenue.

Find everything you need plus a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

COVID-19 Vaccine Available

Through a Federal partnership, Lewis Drug is able to give COVID vaccinations in compliance with state guidelines.

Please do not call your local pharmacy to see if they have vaccine.

SD state guidelines: https://doh.sd.gov/Covid/Vacci...

The 10th & Cliff Sioux Falls, SD Lewis Drug is now offering the COVID-19 vaccine. Click the link below to see if there are any appointments available.

SCHEDULE AN APPOINTMENT

Upcoming Events

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