Get the latest offers and updates from Lewis.

Sign up to receive email alerts on Lewis weekly ads, coupons, in-store events and more.

Lewis - Madison

741 S. Washington Ave., Madison, SD 57042

Explore This Store

741 S. Washington Ave.
Madison, SD 57042

Main Phone:


Store Hours

Mon: 8am - 8pm
Tue: 8am - 8pm
Wed: 8am - 8pm
Thu: 8am - 8pm
Fri: 8am - 8pm
Sat: 8am - 8pm
Sun: 8am - 6pm
Weekly Ad Directions


Pharmacy Phone:


Pharmacy Hours

Mon: 9am - 7pm
Tue: 9am - 7pm
Wed: 9am - 7pm
Thu: 9am - 7pm
Fri: 9am - 7pm
Sat: 9am - 5pm
Sun: 10am - 2pm​

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

View More


The Lewis store in Madison, SD offers the COVID-19 Vaccine.


Walk-in appointments are welcome Tuesday and Wednesday.

Tues: 10am - 6pm
Wed: 10am - 6pm

*Flu vaccine walk-in appointments are available Tuesday, Wednesday, Thursday and Friday from 10am - 6pm.

Call Now

Grab all your everyday essentials from groceries and prescriptions to home decor and beauty supplies at Lewis in Madison. You’ll find a huge selection of name brands and specialty items, all at affordable prices.

Find everything you need and a few unexpected finds with departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

Upcoming Events

Get the latest offers and updates from Lewis.