Lewis Family Drug - De Smet

Explore This Store
De Smet, SD 57231
Main Phone:
605-854-9033Store Hours
Your Family Pharmacy
Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.
This Lewis location has a MedDrop Box available.
Stop by your local Lewis Family Drug, conveniently located in De Smet, and find a large selection everyday essentials, all at affordable prices.
Need to order a prescription? Give our pharmacy a call or quickly and safely refill your prescription with Online or Mobile Refills.
COVID-19 Vaccine Available
Through a Federal partnership, Lewis Drug is able to give COVID vaccinations in compliance with state guidelines.
Please do not call your local pharmacy to see if they have vaccine.
SD state guidelines: https://doh.sd.gov/Covid/Vacci...
The DeSmet, SD Lewis Family Drug is now offering COVID-19 vaccine. Click the link below to see if there are any appointments available.