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Lewis - Brookings

910 22nd Ave S., Brookings, SD 57006
lewis drug exterior

Explore This Store

910 22nd Ave S.
Brookings, SD 57006

Main Phone:


Store Hours

Mon: 8:00am - 8:00pm
Tue: 8:00am - 8:00pm
Wed: 8:00am - 8:00pm
Thu: 8:00am - 8:00pm
Fri: 8:00am - 8:00pm
Sat: 8:00am - 8:00pm
Sun: 8:00am - 6:00pm
Weekly Ad Directions


Pharmacy Phone:


Pharmacy Hours

Mon: 9:00am - 8:00pm
Tue: 9:00am - 8:00pm
Wed: 9:00am - 8:00pm
Thu: 9:00am - 8:00pm
Fri: 9:00am - 8:00pm
Sat: 9:00am - 5:00pm
Sun: 9:00am - 5:00pm​

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

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The Brookings, SD Lewis offers the COVID-19 vaccine.


Walk-in appointments are welcome Monday thru Friday.

Mon: 10am - 6pm
Tue: 10am - 6pm
Wed: 10am - 6pm
Thur: 10am - 6pm
Fri: 10am - 6pm

Call (605) 692-8881 for Saturday and Sunday availability.

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Stop by your local Lewis in Brookings and find a large selection of everyday basics, plus affordable name brands and specialty items.

You'll find everything you’re looking for and a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Lawn & Garden and more.

Upcoming Events

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