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Lewis - 41st & Marion, Sioux Falls

5500 W. 41st St., Sioux Falls, SD 57106

Explore This Store

5500 W. 41st St.
Sioux Falls, SD 57106

Main Phone:

605-367-2000

Store Hours


Mon: 8am - 9pm
Tue: 8am - 9pm
Wed: 8am - 9pm
Thu: 8am - 9pm
Fri: 8am - 9pm
Sat: 8am - 9pm
Sun: 8am - 6pm​
Weekly Ad Directions

Pharmacy

Pharmacy Phone:

605-367-2610

Pharmacy Hours


Mon: 9am - 8pm
Tue: 9am - 8pm
Wed: 9am - 8pm
Thu: 9am - 8pm
Fri: 9am - 8pm
Sat: 9am - 6pm
Sun: 10am - 6pm

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

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Grab all your everyday essentials from groceries and prescriptions to home decor and beauty supplies at your Sioux Falls Lewis, located at 41st Street and Marion Road. You’ll find a huge selection of name brands and specialty items, all at affordable prices.

Find everything you need and a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

Upcoming Events

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