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Lewis - 41st & Marion, Sioux Falls

5500 W. 41st St., Sioux Falls, SD 57106

Explore This Store

5500 W. 41st St.
Sioux Falls, SD 57106

Main Phone:

605-367-2000

Store Hours


Mon: 8:00am - 9:00pm
Tue: 8:00am - 9:00pm
Wed: 8:00am - 9:00pm
Thu: 8:00am - 9:00pm
Fri: 8:00am - 9:00pm
Sat: 8:00am - 9:00pm
Sun: 8:00am - 6:00pm
Weekly Ad Directions

Pharmacy

Pharmacy Phone:

605-367-2610

Pharmacy Hours


Mon: 9:00am - 8:00pm
Tue: 9:00am - 8:00pm
Wed: 9:00am - 8:00pm
Thu: 9:00am - 8:00pm
Fri: 9:00am - 8:00pm
Sat: 9:00am - 6:00pm
Sun: 10:00am - 6:00pm

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

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COVID-19 VACCINE AVAILABLE

The 41st & Marion Rd. Lewis in Sioux Falls, SD offers the COVID-19 Vaccine.

VACCINE CLINIC HOURS:

Walk-in appointments are welcome Monday thru Friday.

Mon: 10am - 6pm
Tues: 10am - 6pm
Wed: 10am - 6pm
Thur: 10am - 6pm
Fri: 10am - 6pm

Call (605) 367-2610 for Saturday & Sunday availability.

Call Now

Grab all your everyday essentials from groceries and prescriptions to home decor and beauty supplies at your Sioux Falls Lewis, located at 41st Street and Marion Road. You’ll find a huge selection of name brands and specialty items, all at affordable prices.

Find everything you need and a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

Upcoming Events

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