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Lewis - 37th & Minnesota, Sioux Falls

2901 S. Minnesota Ave, Sioux Falls, SD 57105

Explore This Store

2901 S. Minnesota Ave
Sioux Falls, SD 57105

Main Phone:

605-367-2000

Store Hours


Mon: 8am - 9pm
Tue: 8am - 9pm
Wed: 8am - 9pm
Thu: 8am - 9pm
Fri: 8am - 9pm
Sat: 8am - 9pm
Sun: 8am - 6pm
Weekly Ad Directions

Pharmacy

Pharmacy Phone:

605-367-2110

Pharmacy Hours


Mon: 9am - 8pm
Tue: 9am - 8pm
Wed: 9am - 8pm
Thu: 9am - 8pm
Fri: 9am - 8pm
Sat: 9am - 6pm
Sun: 10am - 6pm​

Your Family Pharmacy

Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.

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Make your Sioux Falls Lewis your first stop! Our conveniently located store at Minnesota Avenue & 37th Street offers a wide selection of everyday basics, plus name brands and specialty items, always at affordable prices.

You'll find everything on your list along with a few unexpected finds in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.

COVID-19 Vaccine Available

Through a Federal partnership, Lewis Drug is able to give COVID vaccinations in compliance with state guidelines.

Please do not call your local pharmacy to see if they have vaccine.

SD state guidelines: https://doh.sd.gov/Covid/Vacci...

The 37th & Minnesota Ave., SD Lewis Drug is now offering the COVID-19 vaccine. Click the link below to see if there are any appointments available.

SCHEDULE AN APPOINTMENT

Upcoming Events

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