Lewis - 26th & Sycamore, Sioux Falls
Explore This Store
Sioux Falls, SD 57103
Main Phone:
605-367-2000Store Hours
Pharmacy
Pharmacy Phone:
605-367-2710Pharmacy Hours
Your Family Pharmacy
Trusted for decades, ready for the future. Every Lewis pharmacy provides fast and friendly service, from prescription refills to vaccine shots and beyond.
Make Lewis your first stop for your everyday essentials! Our convenient store at 26th Street & Sycamore Avenue offers a wide selection of name brands and specialty items, always at affordable prices.
You'll find everything on your shopping list along with unexpected treasures in departments like Health & Beauty, Grocery, Pets, Wine & Spirits, Lawn & Garden and more.
COVID-19 Vaccine Available
Through a Federal partnership, Lewis Drug is able to give COVID vaccinations in compliance with state guidelines.
Please do not call your local pharmacy to see if they have vaccine.
SD state guidelines: https://doh.sd.gov/Covid/Vacci...
The 26th & Sycamore, SD Lewis Drug is now offering the COVID-19 vaccine. Click the link below to see if there are any appointments available.
