---
title: "Sioux Falls - 10th & Cliff"
date: 2023-05-19T14:54:00-05:00
author: Click Rain Admin
canonical_url: "https://www.lewisdrug.com/locations/sioux-falls-10th-cliff"
section: Locations
---
- ![Pharmacy Icon](https://d1mtm9zwmbt73h.cloudfront.net/general-uploads/icons/pharmacy.png) Pharmacy
- ![Drive Up Icon](https://d1mtm9zwmbt73h.cloudfront.net/general-uploads/icons/drive-up.png) Drive-Up Pharmacy
- ![Store Icon](https://d1mtm9zwmbt73h.cloudfront.net/general-uploads/icons/store.png) Store
 

# Sioux Falls - 10th & Cliff

  [ 1301 E 10th St   
 Sioux Falls, SD 57103 ](https://www.google.com/maps/dir/?api=1&destination=1301%20E%2010th%20St%20Sioux%20Falls%20SD%2057103)  **Store Hours** Mon: 8:00am - 9:00pm Tue: 8:00am - 9:00pm Wed: 8:00am - 9:00pm Thu: 8:00am - 9:00pm Fri: 8:00am - 9:00pm Sat: 8:00am - 9:00pm Sun: 9:00am - 6:00pm ![](/assets/images/icons/store.png) [605-367-2330](tel:605-367-2330) 

 

 **Pharmacy Hours** Mon: 9:00am - 8:00pm Tue: 9:00am - 8:00pm Wed: 9:00am - 8:00pm Thu: 9:00am - 8:00pm Fri: 9:00am - 8:00pm Sat: 9:00am - 6:00pm Sun: 10:00am - 6:00pm ![](/assets/images/icons/pharmacy.png) [605-367-2310](tel:605-367-2310) 

 

 

 

 [ Get Directions](https://www.google.com/maps/dir/?api=1&destination=1301%20E%2010th%20St%20Sioux%20Falls%20SD%2057103) 

 

 [ ](https://www.google.com/maps/dir/?api=1&destination=1301%20E%2010th%20St%20Sioux%20Falls%20SD%2057103) 

  

    ![10th and cliff exterior](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/locations/locations_10th-cliff-OUT.jpg?mode=crop&pos=center-center&w=67&h=43&c=43f1a969&v=2e60691d9275f07ea1fd6ad6d1bed4c8f2ed8fe3e3042088d465114377cc2ca9)   

 

 

 

 

## Sioux Falls 10th & Cliff Reviews

       

You're one stop all place

 Denise wagner November 2020 

      

Just stopped in to use the post office get some stamps and mail a package it's quick and convenient there and if I need something I'm right there to get it

 Bob Oberg November 2020 

       

Neat store and a lot of variety. Love the sales!

 Linda Whitaker December 2020 

 

 

 

  

 

    ![Lewis employee checking out a couple at the register](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/lewis-bg.jpg?mode=fit&pos=center-center&w=38&h=20&c=50339c3e&v=8ce63e0e43d35de083c80895c786c945311b8fde4399c8dd74a0a14beaa3bbc2)      ![A pharmacist flips through a stack of smart packs.](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/featured-callout/23-Lewis_Pharmacy_FeaturedCallout_500x500_1.jpg?mode=crop&pos=center-center&w=50&h=50&c=49beac2a&v=81e4ae7f73607275b9d4a562e2dd275b3f5e9791027298eb7f1f4334a7dc26f9)  

### [Smart Pack](/pharmacy/services#smart-pack)

Pre-sorted, daily dose packets organize medications for convenience.

      ![Lewis Smart Sync Logo](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/featured-callout/23-Lewis_Pharmacy_FeaturedCallout_500x500_2.jpg?mode=crop&pos=center-center&w=50&h=50&c=ba46ec26&v=7326a80cef94d9ac28b69bc3add87e132bb1610f92387aeb0ddc0e6cc813c1c9)  

### [Smart Sync](/pharmacy/prescription-refills#smart-sync)

Synchronize prescription refills to one pickup date for easy management.

      ![A pharmacist takes the lid off of a pill bottle.](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/featured-callout/23-Lewis_Pharmacy_FeaturedCallout_500x500_3.jpg?mode=crop&pos=center-center&w=50&h=50&c=b55c56fd&v=7f274a49986ce714e0edbcb2be22399994ca8a722d6d5763a1eca8f03cbeaaba)  

### [MedDrop Box](/pharmacy/services#meddrop-box)

Stop by Lewis to safely dispose of expired, unused, or unwanted medication.

      ![A pharmacist puts on a surgical mask.](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/featured-callout/23-Lewis_Pharmacy_FeaturedCallout_500x500_4.jpg?mode=crop&pos=center-center&w=50&h=50&c=67cff790&v=b1fa5b6a0403f9620a113223442a5190580d242b6165be474063eb31df0519ab)  

### [COVID-19](https://www.lewisdrug.com/pharmacy/immunizations/covid-19)

Lewis Pharmacy offers quality COVID-19 care, including testing services.

      ![A person shows their vaccinated arm with a band-aid.](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/featured-callout/23-Lewis_Pharmacy_FeaturedCallout_500x500_5.jpg?mode=crop&pos=center-center&w=50&h=50&c=8dbed017&v=de1cea4442c7d2fbd559c35001432c9eee24a855ee1408383f32672fd8788547)  

### [Immunizations](https://www.lewisdrug.com/pharmacy/immunizations)

Make Lewis Pharmacy your destination for flu shots and flu season essentials.

      ![A patient speaks with a pharmacist.](https://d37vnv41mw7wpr.cloudfront.net/generalUploads/featured-callout/23-Lewis_Pharmacy_FeaturedCallout_500x500_6.jpg?mode=crop&pos=center-center&w=50&h=50&c=193c1c2a&v=f7b6a4dbcd321410534e77cfbadc8b8b01bcce0df8ddc890593364c8a129c121)  

### [Screenings](/pharmacy/services#screenings)

We offer important health screenings for your family's preventative care needs.

  

 

 

## Weekly Ad for 10th & Cliff

  

 

   December 13 

### Santa Event - 10th & Cliff Ave.

  Sioux Falls - 10th & Cliff  

 [Learn More ![](/assets/images/icons/arrow.svg)](https://www.lewisdrug.com/events/santa-event-10th-cliff-ave)